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. Author manuscript; available in PMC: 2018 Dec 15.
Published in final edited form as: Gene Ther. 2018 Jun 15;25(5):359–375. doi: 10.1038/s41434-018-0022-y

Figure 3. Quantitative bacterial culture from blood and lungs after PNA challenge and treatment with EP-mediated delivery of FER gene.

Figure 3.

Number of CFUs of bacteria were counted 16 h after processing on blood agar plates and normalized to 1 ml of blood and to mass of total lung tissue respectively. EP of FER gene was able to contain and avoid systemic dissemination in blood and eliminate infection by 72 h. in the lung. N=10 animals per group per time point. Significance placed in graph. One-way ANOVA with Tukey’s multiple comparison tests (* p < 0.05; ** p < 0.01; *** p < 0.001).