Figure - PMC

Skip to main content

View full-text article in PMC

. Author manuscript; available in PMC: 2019 Nov 1.

Published in final edited form as: Hepatology. 2018 Jul 10;68(5):1890–1904. doi: 10.1002/hep.30051

B cell development in the normal neonatal liver and spleen. A. Diagram of B cell surface marker expression during B cell maturation. Thicker lines denote higher levels of expression. B. Representative contour plots of B cell subsets in 7 day old liver and spleen (gated on live cells, FSC/SSC lymphocytes, CD45⁺cells, B220/ CD19⁺ cells). C. Summary of B cell subset frequencies in the liver and spleen of 2 day, 7 day and 14 day old mice (gated on live, FSC/SSC, CD45⁺, B220/ CD19⁺ cells; note that first set of bar graphs is B220/CD19⁺ cells gated on live, FSC/SSC and CD45⁺ cells). Imm: immature, TR: transitional, TR2: transitional-2, Mat: mature. ***p < 0.0005; **p < 0.005; *p < 0.05

B cell development in the normal neonatal liver and spleen. A. Diagram of B cell surface marker expression during B cell maturation. Thicker lines denote higher levels of expression. B. Representative contour plots of B cell subsets in 7 day old liver and spleen (gated on live cells, FSC/SSC lymphocytes, CD45⁺cells, B220/ CD19⁺ cells). C. Summary of B cell subset frequencies in the liver and spleen of 2 day, 7 day and 14 day old mice (gated on live, FSC/SSC, CD45⁺, B220/ CD19⁺ cells; note that first set of bar graphs is B220/CD19⁺ cells gated on live, FSC/SSC and CD45⁺ cells). Imm: immature, TR: transitional, TR2: transitional-2, Mat: mature. ***p < 0.0005; **p < 0.005; *p < 0.05