Table 3.
Hematological values of rats after 28-day exposure of Al2O3 nanoparticles
| Parameter | Dose (mg/m3) | |||
|---|---|---|---|---|
|
| ||||
| 0 | 0.2 | 1 | 5 | |
| No. of animals | 8 | 8 | 8 | 8 |
| RBC (106/μL) | 8.10 ± 0.29 | 8.49 ± 0.49 | 8.42 ± 0.31 | 8.28 ± 0.23 |
| Hemoglobin (g/dL) | 14.49 ± 0.38 | 14.96 ± 0.77 | 14.94 ± 0.44 | 14.73 ± 0.32 |
| Hematocrit (%) | 41.54 ± 1.06 | 43.35 ± 2.21 | 43.05 ± 1.39 | 42.76 ± 1.12 |
| MCV (fL) | 51.29 ± 1.28 | 51.10 ± 1.11 | 51.18 ± 1.00 | 51.65 ± 0.63 |
| MCH (pg) | 17.89 ± 0.61 | 17.64 ± 0.54 | 17.75 ± 0.40 | 17.79 ± 0.30 |
| MCHC (g/dL) | 34.86 ± 0.31 | 34.50 ± 0.37 | 34.69 ± 0.16 | 34.43 ± 0.36 |
| RDW (%) | 13.21 ± 0.78 | 12.85 ± 0.92 | 13.20 ± 1.00 | 12.78 ± 0.77 |
| Platelet (103/μL) | 1032.63 ± 115.25 | 1045.38 ± 106.94 | 1035.88 ± 62.60 | 980.38 ± 59.89 |
| MPV (fL) | 7.36 ± 0.44 | 7.35 ± 0.40 | 7.44 ± 0.37 | 7.64 ± 0.29 |
| WBC (103/μL) | 5.08 ± 1.21 | 4.78 ± 0.78 | 5.41 ± 1.11 | 5.52 ± 0.64 |
| Neutrophils (103/μL) | 1.17 ± 0.29 | 1.19 ± 0.32 | 1.31 ± 0.20 | 1.51 ± 0.33 |
| Lymphocytes (103/μL) | 3.73 ± 1.01 | 3.42 ± 0.97 | 3.89 ± 0.91 | 3.81 ± 0.53 |
| Monocytes (103/μL) | 0.08 ± 0.04 | 0.07 ± 0.02 | 0.09 ± 0.03 | 0.09 ± 0.02 |
| Eosinophils (103/μL) | 0.06 ± 0.02 | 0.06 ± 0.02 | 0.07 ± 0.01 | 0.06 ± 0.01 |
| Basophils (103/μL) | 0.01 ± 0.01 | 0.01 ± 0.00 | 0.01 ± 0.01 | 0.01 ± 0.00 |
RBC, red blood cell count; MCV, mean corpuscular volume; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; RDW, red cell distribution width; MPV, mean platelet volume; WBC, white blood cell count.
Values are expressed as means ± SD.