Table 5.
Serum biochemical values of rats after 28-day exposure of Al2O3 nanoparticles
| Parameter | Dose (mg/m3) | |||
|---|---|---|---|---|
|
| ||||
| 0 | 0.2 | 1 | 5 | |
| No. of animals | 8 | 8 | 8 | 8 |
| AST (IU/L) | 105.06 ± 23.01 | 110.49 ± 43.87 | 100.30 ± 21.83 | 113.68 ± 23.94 |
| ALT (IU/L) | 51.41 ± 9.90 | 51.24 ± 9.05 | 46.46 ± 7.17 | 51.68 ± 6.35 |
| ALP (IU/L) | 971.38 ± 223.04 | 1110.54 ± 26.71 | 979.93 ± 87.44 | 1010.43 ± 20.96 |
| CPK (IU/L) | 533.18 ± 271.21 | 631.91 ± 220.95 | 782.96 ± 323.25 | 682.56 ± 266.52 |
| LDH (IU/L) | 1789.49 ± 942.80 | 2088.69 ± 838.93 | 2317.25 ± 957.19 | 2385.49 ± 1021.01 |
| TBil (mg/dL) | 0.17 ± 0.04 | 0.17 ± 0.02 | 0.16 ± 0.04 | 0.17 ± 0.03 |
| Glucose (mg/dL) | 142.20 ± 47.45 | 128.56 ± 12.83 | 130.38 ± 16.83 | 129.09 ± 18.48 |
| TCho (mg/dL) | 80.19 ± 40.16 | 68.93 ± 8.48 | 74.34 ± 10.43 | 68.41 ± 6.04 |
| Triglyceride (mg/dL) | 70.91 ± 42.38 | 48.49 ± 9.25 | 49.80 ± 14.73 | 46.36 ± 15.96 |
| TP (g/dL) | 5.89 ± 0.29 | 5.94 ± 0.13 | 5.93 ± 0.26 | 5.89 ± 0.15 |
| Albumin (g/dL) | 4.04 ± 0.27 | 4.11 ± 0.10 | 4.11 ± 0.08 | 4.19 ± 0.10 |
| BUN (mg/dL) | 15.46 ± 3.20 | 15.83 ± 1.49 | 14.99 ± 2.92 | 15.65 ± 2.16 |
| Creatinine (mg/dL) | 0.41 ± 0.04 | 0.40 ± 0.03 | 0.40 ± 0.02 | 0.41 ± 0.02 |
| IP (mg/dL) | 7.84 ± 0.55 | 7.98 ± 0.74 | 7.84 ± 0.94 | 8.01 ± 0.42 |
| Ca (mg/dL) | 9.19 ± 0.25 | 9.31 ± 0.24 | 9.35 ± 0.28 | 9.38 ± 0.28 |
AST, aspartate aminotransferase; ALT, alanine aminotransferase; ALP, alkaline phosphatase; CPK, creatine phosphokinase; LDH, lactate dehydrogenase; TBil, total bilirubin; TCho, total cholesterol; TP, total protein; BUN, blood urea nitrogen; IP, inorganic phosphorus; Ca, calcium.
Values are expressed as means ± SD.