Table 7.

Absolute and relative organ weights of rats after 28-day exposure of Al₂O₃ nanoparticles

Parameter	Dose (mg/m3)
	0	0.2	1	5
No. of animals	8	8	8	8
Body weight (g)	331.07 ± 19.77	326.94 ± 24.48	333.43 ± 12.98	335.11 ± 12.24
Lung	1.829 ± 0.142	1.761 ± 0.119	1.839 ± 0.093	2.040 ± 0.073**
per body weight (%)	0.615 ± 0.048	0.592 ± 0.040	0.619 ± 0.031	0.686 ± 0.024**
Liver (g)	10.381 ± 1.034	9.783 ± 0.788	10.031 ± 0.899	9.822 ± 0.705
per body weight (%)	3.492 ± 0.348	3.291 ± 0.265	3.375 ± 0.302	3.304 ± 0.237
Kidney	2.172 ± 0.267	1.997 ± 0.182	2.022 ± 0.121	2.028 ± 0.137
per body weight (%)	0.731 ± 0.090	0.672 ± 0.061	0.680 ± 0.041	0.682 ± 0.046
Spleen (g)	0.602 ± 0.034	0.579 ± 0.044	0.623 ± 0.111	0.651 ± 0.046
per body weight (%)	0.202 ± 0.011	0.195 ± 0.015	0.210 ± 0.037	0.219 ± 0.016
Brain (g)	1.976 ± 0.074	2.012 ± 0.086	1.941 ± 0.067	2.053 ± 0.170
per body weight (%)	0.665 ± 0.025	0.677 ± 0.029	0.653 ± 0.023	0.691 ± 0.057

Values are expressed as means ± SD.

^**Significantly different from vehicle control at p<0.01.