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. 2018 Oct 15;34(4):291–296. doi: 10.5487/TR.2018.34.4.291

Fig. 5.

Fig. 5

Dose-response plots and derived BMDL10 values for DNA adducts, mutations, GST-P positive foci, and hepatocellular adenoma and carcinoma in the liver of F344 rats treated with MeIQx at various doses (12). BMDL10, lower 95% confidence limit of the benchmark dose corresponding to a 10% extra risk; GST-P, glutathione S-transferase placental form; MeIQx, 2-amino-3,8-dimethylimidazo-(4,5-f)quinoxaline.