Table 1. Histopathological characteristics of our cases of pulmonary and mediastinal paragangliomas.
Patients | Localization | Capsule | Hypervascularization | NSE | CgA | Synaptophysin | S-100 protein | Vimentin | CKs | Ki-67 | Mitotic count (n/10 HPF) |
---|---|---|---|---|---|---|---|---|---|---|---|
Case 1 | Pulmonary | Yes | Yes | + | − | +++ | +++ | n.t. | − | 5% | 2 |
Case 2 | Pulmonary | Incomplete | Yes | + | + | + | ++ | + | − | >40% | 25 |
Case 3 | Mediastinal | Incomplete | Yes | n.t. | +++ | +++ | +++ | n.t. | − | 10% | 7 |
n.t., not tested.