Table 2. Diagnostic criteria of pulmonary vasculitis.
| Disease | Diagnostic criteria |
|---|---|
| Takayasu’s arteritisa | Age at onset <40 years |
| One extremity claudication | |
| Decreased brachial artery pulse | |
| >10 mmHg difference in systolic arterial pressure between both arms | |
| Subclavian or aortic murmur | |
| Arteriography shows narrowing or occlusion of the aorta, its primary branches or large arteries in the proximal part of the upper or lower extremities | |
| Giant cell arteritisa | Age at onset >50 years |
| New start cephalea | |
| Abnormality in the temporal artery (sensitivity or pulse diminished) | |
| Sedimentation rate ≥50 mm/h | |
| Abnormal artery biopsy: vasculitis characterised by mononuclear cell infiltration or granulomatous inflammation with multinucleated giant cells | |
| Granulomatosis with polyangiitisb | Nasal or oral inflammation |
| Abnormal thoracic X-ray | |
| Active urinary sediment | |
| Granulomatous inflammation in the biopsy | |
| Polyarteritis nodosac | Weight loss <4 kg since the disease onset |
| Livedo reticularis | |
| Testicular pain or sensitivity | |
| Myalgias, sensitivity or leg pain | |
| Mono or polyneuropathy | |
| Diastolic arterial pressure >90 mmHg | |
| Nitrogenated urea >40 mg/dL or creatinine >1.5 mg/dL | |
| Hepatitis B virus acute infection | |
| Arteriographic abnormalities | |
| Medium or small vessel artery biopsy with polymorphonuclear leukocytes | |
| Microscopic polyangiitis | No differences with polyarteritis nodosa |
| Eosinophilic granulomatosis with polyangiitisd | Asthma |
| Eosinophilia | |
| Mono o polyneuropathy | |
| Pulmonary infiltration | |
| Paranasal sinus alteration | |
| Extravascular eosinophils | |
| Anti-basement membrane antibody disease | Glomerular anti-basement membrane antibody disease (in serum or tissue) |
| Crescentic proliferative glomerulonephritis | |
| Lineal deposit of immunoglobulin G in the glomerular basement membrane (direct immunofluorescence) | |
| With/without alveolar haemorrhage evidence | |
| Cryoglobulinemic vasculitis | Finding cryoglobulinemia in the context of suggestive symptoms for vasculitis (purpura, peripheral neuropathy or glomerulonephritis) |
| IgA vasculitis (Henoch-Schönlein)a | Age ≤20 years |
| Tangible purpura | |
| Severe abdominal pain | |
| Biopsy that shows granulocytes in small vessel walls | |
| Hypocomplementemic urticarial vasculitise | Major criteria |
| ❖ Urticarial vasculitis skin lesions | |
| ❖ Seric hypocomplementemia | |
| Minor criteria | |
| ❖ Dermic venulitis proved by biopsy | |
| ❖ Arthritis or arthralgias | |
| ❖ Uveitis or episcleritis (or conjunctivitis) | |
| ❖ Mild glomerulonephritis | |
| ❖ Recurrent abdominal pain | |
| ❖ Anti-C1q antibodies associated to reduce seric levels of C1q | |
| Behçet diseasef | Recurrent oral ulcers |
| Recurrent genital ulcers | |
| Ocular lesions | |
| Cutaneous lesions | |
| Positive patergia test |
a, should show at least 3 criteria; b, should show 2 or more criteria; c, diagnosis requires the integration of clinical, angiographic, and biopsy findings; d, should show 4 or more criteria; e, should show 2 major criteria and at least 2 minor criteria; f, should show the first criteria and at least 2 of the next ones.