Table 2. TAUR treatment improves cardiac function after MI.
Group | Vehicle-sham (n=6) | TAUR-sham (n=6) | Vehicle-MI (n=6) | TAUR-MI (n=6) |
---|---|---|---|---|
EF | 75.95±8.31 | 65.08±6.84 | 43.44±7.86* | 55.93±4.28† |
FS | 44.66±7.96 | 35.27±5.27 | 21.62±4.55* | 29.17±2.76† |
IVSd | 1.43±0.12 | 1.53±0.26 | 1.08±0.13* | 1.06±0.23 |
IVSs | 0.83±0.10 | 0.97±0.14 | 0.73±0.08* | 0.70±0.12 |
LVIDd | 3.78±0.51 | 3.74±0.43 | 4.86±0.46* | 4.62±0.32 |
LVIDs | 2.10±0.47 | 2.42±0.37 | 3.81±0.48* | 3.27±0.31† |
LVPWd | 0.75±0.13 | 0.81±0.10 | 0.72±0.09 | 0.78±0.16 |
LVPWs | 1.37±0.30 | 1.16±0.17 | 0.94±0.11* | 1.02±0.24 |
LV Mass | 105.43±14.97 | 123.47±27.68 | 144.65±32.79 | 138.56±39.78 |
LV VOLd | 62.68±20.81 | 60.86±16.08 | 111.92±24.5* | 98.82±16.51 |
LV VOLs | 15.55±8.14 | 21.47±8.29 | 64.00±19.1* | 43.88±9.71 |
HR | 504±50 | 474±40 | 449±42 | 459±43 |
EF, ejection fraction; FS, fractional shortening; IVSs, interventricular septum wall thickness in end-systole; IVSd, interventricular septum wall thickness in end-diastole; LVIDd, left ventricle end-diastolic inner diameter; LVIDs, left ventricle end-systolic inner diameter; LVPWs, left ventricle posterior wall thickness in end-systole; LVPWd, left ventricle posterior wall thickness in end-diastole; LV VOLd, LV volumes at end-diastole; LV VOLs, LV volumes at end-systole; HR, heart rate. Data are presented as mean ± SD, n=6 per group. *, P<0.05 versus corresponding sham group; †, P<0.05 versus vehicle-MI group.