FIGURE 3.
Responses of MAP and HR evoked by static muscle contraction and passive tendon stretch. (A) Muscle contraction was evoked by electrical stimulation of the L4 and L5 ventral roots. Femoral artery occlusion enhanced MAP and HR responses as compared with control rats. In occluded rats (n = 10), PTX significantly inhibited amplification of MAP responses induced by muscle contraction. ∗P < 0.05, compared with control rats and †P < 0.05, compared with occluded rats without PTX (n = 8 in each group). No significant differences were seen in muscle developed tension among three groups. For example, 535 ± 30 g in control, 547 ± 28 g in occluded rats, and 550 ± 35 g in occluded rats with PTX. (B) Showing that femoral artery occlusion amplified MAP response induced by the passive tendon stretch, but PTX failed to attenuate amplification of MAP response (P > 0.05, occlusion vs. occlusion plus PTX; n = 6 in each group). Muscle tension was ∼500 g. ∗P < 0.05, compared with control rats (n = 8).