Table 2.
List of undetected inflammatory genes in conjunctival cells from CI samples collected in DED patients.
| n | Gene name | |
|---|---|---|
| MHC and cell surface receptor | 2 | FXYD2, TBXA2R |
| IFN and ISGs | 2 | IFNA1, IFNB1 |
| Chemokines and receptors | 9 | CCL2, CCL7, CCL8, CCL11, CCL16, CCL19, CCL21, CCL23, CCR3 |
| Interleukins and receptors | 9 | IL1A, IL2, IL9, IL10, IL11, IL12B, IL13, IL21, TSLP |
| Prostaglandin receptors | 4 | PTGIR, PTGS1, PTGER3, PTGDR2 |
| Toll-like receptors | 2 | TLR7, TLR9 |
| TGF | 2 | TGFB2, TGFB3 |
| VEGF | 1 | FLT1 |
| Leukotrien receptors | 1 | CYSLTR2 |
| Complement and CRP | 8 | C5, C6, C7, C8A, C8B, C9, MASP1, MASP2 |
| Enzymes | 2 | ALOX12, ARG1 |
| Adaptor proteins | 2 | MBL2, MYL2 |
| Co-factors | 1 | KNG1 |
| CSF | 1 | CSF2 |
| MMP | 1 | MMP3 |
| Transcription factors | 2 | MEF2B,TWIST2 |
A total RNA of 100 ng was analyzed on the nCounter® human inflammation v2 chip containing 249 unique fluorescent barcoded probes to detect mRNA abundance. Forty-nine genes were not detected. Genes were classified according to their family.