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Correlations between vaccination responses and IgG-subclass levels. The graphs show the Spearman's correlation coefficients and 95% confidence interval (CI) for IgG1-4 vs. vaccination responses. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001. DIP, diphtheria; TET, tetanus; PVR, pneumococcal vaccination response.
