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Systemic cytokine expression in human CD52Tg cardiac allograft recipients after alemtuzmab treatment. Pre- and Post-transplant level of (A) IL-21, (B) IL-4, (C) BAFF, and (D) IL-2 were measured from serum. IL-4 and IL-21 levels were significantly reduced by anti-LFA-1 mAb treatment at (E) Post-transplant 2 weeks and (F) post-transplant 14 weeks. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.
