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. 2018 Feb 1;17(4):325–330. doi: 10.2463/mrms.mp.2017-0072

Table 1.

Short-term imaging findings in patients with giant cell tumors of the bone who were treated with denosumab

No. Sex Age Location Pretreatment Tumor size (mm) Size of cystic component (mm) SI ratio on T2 weighted image New bone formation ADC value (10−3 × mm2/sec)




Pre Post Pre Post Pre Post Pre Post
1 M 37 Tibia 60 50 43 18 3.6 2.9 + 1.03 0.66
2 M 26 Humerus 66 55 39 15 9.7 3.6 + 1.55 1.33
3 M 33 Carpus 25 22 10 0 4.9 1.1 + 1.25 1.29
4 M 52 Vertebra 32 30 15 15 10.7 0.9 + 1.66 2.24
5 M 41 Skull bone 46 20 40 12 3.5 2.7 2.60 1.74
6 F 34 Vertebra 23 22 0 0 2.2 1.7 + 0.91 1.23
7 M 54 Radius Curettage with bone grafting 25 24 0 0 1.2 1.1 + N/A N/A
8 M 34 Femur Curettage with bone grafting 64 60 0 0 1.3 0.8 + N/A N/A
9 F 26 Vertebra Curettage alone 89 87 0 0 2.4 1.6 N/A N/A
10 F 51 Vertebra Curettage alone 30 24 0 0 2.2 1.3 N/A N/A
11 F 39 Vertebra Curettage alone 31 30 0 0 2.2 1.7 N/A N/A
12 F 66 Sacrum Embolization 74 63 0 0 3.4 3 N/A N/A

ADC, apparent diffusion coefficient; SI ratio, the signal intensity ratio between the solid part of the tumor and muscle.