Table 3.

Expression kinetics of 21 transcripts significantly induced or repressed in human monocyte derived macrophages of eight donors after 4 h infection with an L. braziliensis isolate of a cutaneous leishmaniasis patient from Corte de Pedra, Brazil.

Transcript	4 h Mean (SE)	24 h Mean (SE)	48 h Mean (SE)	4 h × 24 h × 48 h p-value	4 h × 24 h p-value	4 h × 48 h p-value
LRRK2	0.44 (0.11)	0.64 (0.19)	0.30 (0.09)	0.2637	0.3751	0.3565
NUP214	0.55 (0.07)	1.17 (0.10)	0.86 (0.21)	0.0162*	0.0008***	0.1407
TRERF1	0.55 (0.11)	1.58 (0.40)	1.01 (0.27)	0.1443	0.0484*	0.1874
TP53	0.60 (0.10)	0.88 (0.15)	0.73 (0.19)	0.3708	0.1747	0.6276
IL10RB	0.60 (0.13)	1.18 (0.09)	0.53 (0.17)	0.0395*	0.0087**	0.8201
MAPK14	0.62 (0.12)	0.89 (0.21)	0.71 (0.17)	0.3497	0.2053	0.6732
TLR8	0.68 (0.15)	1.23 (0.29)	0.53 (0.18)	0.1667	0.2021	0.4237
NDUFA11	0.70 (0.08)	2.11 (0.57)	0.57 (0.19)	0.0490*	0.0430*	0.5232
PARK7	0.73 (0.05)	1.23 (0.07)	0.76 (0.19)	0.0304*	0.0001***	0.8683
XPO6	0.77 (0.10)	1.56 (0.47)	0.94 (0.30)	0.2905	0.1462	0.6111
MYD88H	0.85 (0.11)	1.64 (0.26)	0.68 (0.17)	0.0104*	0.0384*	0.4681
FRP1	0.86 (0.27)	1.61 (0.26)	0.94 (0.23)	0.1498	0.1212	0.8445
NUP93	1.02 (0.24)	1.06 (0.05)	0.98 (0.23)	0.9414	0.8573	0.9014
IL15RA	1.32 (0.40)	1.37 (0.28)	0.92 (0.22)	0.5385	0.9363	0.4214
NUB1	1.35 (0.37)	2.40 (0.56)	0.86 (0.27)	0.0929	0.2262	0.3887
UBC	1.39 (0.30)	3.27 (0.82)	0.77 (0.21)	0.0244*	0.0154*	0.1336
TXRND1	1.85 (0.28)	2.44 (0.68)	0.87 (0.25)	0.0621	0.3381	0.0730
MT1X	2.66 (0.69)	1.50 (0.30)	1.24 (0.41)	0.1087	0.1084	0.1095
MT1M	3.20 (0.71)	3.25 (1.04)	0.78 (0.29)	0.0214*	0.9564	0.0058**
HSPA1A	4.45 (2.14)	2.84 (0.90)	2.43 (1.44)	0.6523	0.5278	0.5245

Statistical comparisons of three time points were done by ANOVA; comparisons between two times utilized Student’s t-test. ^∗p < 0.05; ^∗∗p < 0.01; ^∗∗∗p < 0.001.