Fig. 8.

A. A pictorial of the relationships between core and preferred ambient temperature for a mouse and human wearing personal protective equipment (PPE) commonly used in an animal vivarium at a ambient temperature of 20 °C. Under these conditions, the gradient between core and ambient temperature is ideal for the human but a cold stress for the mouse. B. Raising ambient temperature to 30 °C reduces the gradient for both mouse and human creating a situation of ideal thermal comfort for the mouse but relatively uncomfortable heat stress for the human wearing PPE.