Table 2.
Univariate Cox regression analysis of overall survival, bleeding-free survival and disease-specific survival
| Parameter |
OS |
BFS |
DSS |
|||||||||
| B | P value | RR | 95%CI | B | P value | RR | 95%CI | B | P value | RR | 95%CI | |
| Type of operation | 0.16 | 0.62 | 1.18 | 0.62-2.23 | -0.39 | 0.33 | 0.68 | 0.31-1.48 | -0.45 | 0.17 | 0.64 | 0.34-1.21 |
| CCI | 0.04 | 0.00 | 1.04 | 1.01-1.07 | 0.02 | 0.36 | 1.02 | 0.98-1.05 | 0.06 | 0.00 | 1.06 | 1.02-1.09 |
| Gender | 0.01 | 0.99 | 1.01 | 0.54-1.89 | 0.94 | 0.02 | 2.56 | 1.20-5.43 | 0.06 | 0.91 | 1.06 | 0.43-2.60 |
| Age | 0.06 | 0.00 | 1.06 | 1.03-1.09 | 0.04 | 0.01 | 1.05 | 1.01-1.08 | 0.05 | 0.00 | 1.05 | 1.02-1.09 |
| Aetiology | 0.07 | 0.74 | 1.07 | 0.73-1.56 | 0.16 | 0.44 | 1.18 | 0.78-1.78 | -0.16 | 0.43 | 0.86 | 0.58-1.26 |
| History of variceal ligation | 0.75 | 0.10 | 2.12 | 0.87-5.19 | 1.07 | 0.01 | 2.92 | 1.24-6.88 | 0.54 | 0.21 | 1.72 | 0.73-4.02 |
| History of abdominal surgery | 0.33 | 0.42 | 1.39 | 0.63-3.03 | 0.16 | 0.73 | 1.17 | 0.48-2.87 | -1.28 | 0.20 | 0.28 | 0.04-1.96 |
| Smoking | 0.45 | 0.19 | 1.56 | 0.80-3.04 | 0.54 | 0.15 | 1.72 | 0.82-3.60 | 0.27 | 0.55 | 1.31 | 0.55-3.11 |
| Drinking | 0.17 | 0.65 | 1.19 | 0.56-2.51 | 0.71 | 0.07 | 2.04 | 0.96-4.33 | -0.12 | 0.81 | 0.89 | 0.34-2.35 |
| Charlson Score | 0.11 | 0.53 | 1.12 | 0.80-1.56 | 0.02 | 0.93 | 1.02 | 0.69-1.51 | 0.06 | 0.77 | 1.06 | 0.72-1.58 |
| History of variceal bleeding | 0.07 | 0.82 | 1.08 | 0.57-2.03 | 1.02 | 0.01 | 2.77 | 1.30-5.90 | -0.30 | 0.43 | 0.74 | 0.36-1.55 |
| Blood type | -0.20 | 0.25 | 0.82 | 0.58-1.15 | -0.15 | 0.41 | 0.86 | 0.60-1.23 | -0.16 | 0.29 | 0.85 | 0.63-1.15 |
| BMI | -0.06 | 0.34 | 0.94 | 0.83-1.07 | 0.00 | 0.97 | 1.00 | 0.88-1.14 | -0.03 | 0.57 | 0.97 | 0.86-1.09 |
| Total hospital stay | 0.01 | 0.36 | 1.01 | 0.99-1.04 | 0.00 | 0.79 | 1.00 | 0.98-1.03 | -0.03 | 0.26 | 0.97 | 0.93-1.02 |
| Duration of preoperative hospital stay | 0.01 | 0.43 | 1.01 | 0.98-1.05 | 0.01 | 0.59 | 1.01 | 0.97-1.05 | 0.04 | 0.20 | 1.04 | 0.98-1.09 |
| Duration of postoperative hospital stay | 0.03 | 0.20 | 1.03 | 0.98-1.09 | -0.01 | 0.71 | 0.99 | 0.92-1.06 | 0.00 | 0.91 | 1.00 | 0.94-1.08 |
| Operative time | 0.01 | 0.00 | 1.01 | 1.00-1.02 | 0.01 | 0.04 | 1.01 | 1.00-1.02 | 0.00 | 0.33 | 1.00 | 1.00-1.01 |
| Intraoperative blood loss | 0.00 | 0.01 | 1.00 | 1.00-1.01 | 0.00 | 0.00 | 1.00 | 1.00-1.01 | 0.00 | 0.09 | 1.00 | 1.00-1.00 |
| Time to first flatus | -0.01 | 0.94 | 0.99 | 0.81-1.21 | 0.23 | 0.03 | 1.26 | 1.03-1.53 | -0.06 | 0.57 | 0.94 | 0.78-1.15 |
| WBC count | 0.20 | 0.03 | 1.22 | 1.02-1.45 | 0.15 | 0.13 | 1.16 | 0.96-1.41 | -0.02 | 0.88 | 0.98 | 0.80-1.21 |
| Hb | -0.01 | 0.04 | 0.99 | 0.97-1.00 | -0.02 | 0.04 | 0.99 | 0.97-1 | -0.01 | 0.31 | 0.99 | 0.97-1.01 |
| Platelet count | 0.01 | 0.08 | 1.01 | 1.00-1.02 | 0.01 | 0.01 | 1.01 | 1.00-1.02 | 0.01 | 0.05 | 1.01 | 1.00-1.03 |
| PT | 0.07 | 0.46 | 1.07 | 0.90-1.27 | -0.08 | 0.44 | 0.92 | 0.74-1.14 | -0.26 | 0.75 | 0.77 | 0.16-3.66 |
| INR | -0.03 | 0.93 | 0.97 | 0.51-1.83 | -0.93 | 0.44 | 0.39 | 0.04-4.29 | -1.80 | 0.84 | 0.17 | 0.00-9821579.13 |
| TBIL | 0.01 | 0.22 | 1.01 | 0.99-1.03 | -0.01 | 0.45 | 0.99 | 0.97-1.02 | 0.00 | 0.97 | 1.00 | 0.96-1.04 |
| DBIL | 0.02 | 0.20 | 1.02 | 0.99-1.06 | -0.03 | 0.34 | 0.97 | 0.92-1.03 | 0.02 | 0.72 | 1.02 | 0.93-1.12 |
| ALT | 0.00 | 0.00 | 1.00 | 1.00-1.01 | -0.01 | 0.35 | 0.99 | 0.98-1.01 | 0.01 | 0.12 | 1.02 | 1.00-1.03 |
| AST | 0.00 | 0.01 | 1.00 | 1.00-1.01 | -0.02 | 0.10 | 0.98 | 0.96-1.00 | -0.01 | 0.27 | 0.99 | 0.97-1.01 |
| ALB | -0.11 | 0.00 | 0.90 | 0.84-0.96 | -0.03 | 0.45 | 0.98 | 0.91-1.04 | -0.39 | 0.25 | 0.68 | 0.35-1.31 |
| GLB | 0.02 | 0.53 | 1.02 | 0.96-1.07 | -0.07 | 0.04 | 0.93 | 0.87-1.00 | 0.03 | 0.28 | 1.03 | 0.97-1.10 |
| Scr | 0.01 | 0.32 | 1.01 | 0.99-1.03 | 0.02 | 0.07 | 1.02 | 1.00-1.03 | -0.08 | 0.01 | 0.93 | 0.87-0.98 |
| Cys C | 0.71 | 0.09 | 2.03 | 0.91-4.57 | 0.23 | 0.67 | 1.26 | 0.44-3.66 | 1.17 | 0.02 | 3.21 | 1.20-8.62 |
| Child-Pugh score | 0.29 | 0.01 | 1.33 | 1.08-1.65 | 0.13 | 0.36 | 1.13 | 0.87-1.48 | 0.14 | 0.54 | 1.15 | 0.74-1.81 |
| MELD score | 0.50 | 0.18 | 1.64 | 0.80-3.40 | 0.02 | 0.97 | 1.02 | 0.44-2.36 | 4.18 | 0.05 | 65.31 | 0.94-4536.32 |
| ALBI score | 1.07 | 0.00 | 2.92 | 1.49-5.76 | 0.19 | 0.59 | 1.21 | 0.60-2.46 | -3.86 | 0.33 | 0.02 | 0.00-48.67 |
OS: Overall survival; BFS: Bleeding-free survival; CCI: Comprehensive Complication Index; BMI: Body mass index; WBC: White blood cell; Hb: Haemoglobin; PT: Prothrombin time; INR: International normalised ratio; TBIL: Total bilirubin; DBIL: Direct bilirubin; ALT: Alanine transaminase; AST: Aspartate transaminase; ALB: Albumin; GLB: Globulin; Scr: Serum creatinine; Cys C: Cystatin C; MELD: Model for end-stage liver disease; ALBI: Albumin-bilirubin; B: Regression coefficient; SE: Standard error; RR: Relative risk; CI: Confidence interval.