Table 1.

Number of Cases and National Estimates of Emergency Department Visits for Dietary Supplement Adverse Events—United States, 2004–2013^*

Characteristics	Emergency Department Visits for Dietary Supplement Adverse Events
	Cases, No.	Annual Estimate
		No.	%	95% Confidence Interval
Age (years)
≤4	988	4,965	21.6	18.9 – 24.3
5–10	126	697	3.0	2.3 – 3.7
11–19	308	1,866	8.1	6.7 – 9.6
20–34	930	6,433	28.0	25.1 – 30.8
35–49	558	3,505	15.2	13.6 – 16.8
50–64	399	2,682	11.7	9.8 – 13.5
≥65	358	2,857	12.4	10.1 – 14.7
Sex
Female	2,121	13,402	58.3	56.4 – 60.1
Male	1,546	9,602	41.7	39.9 – 43.6
Race
Black	577	2,547	11.1	6.6 – 15.6
White	1,586	11,710	50.9	40.6 – 61.2
Other	552	3,166	13.8	7.5 – 20.1
Unknown	952	5,581	24.3	15.2 – 33.3
Number of implicated products
One supplement implicated	3,203	20,303	88.3	86.3 – 90.2
>1 Supplement implicated	97	536	2.3	1.5 – 3.1
Supplement and non-supplement implicated	367	2,165	9.4	7.6 – 11.2
Mechanism of adverse event†
Adverse reaction	1,152	7,663	33.3	29.9 – 36.7
Allergic reaction	796	5,434	23.6	21.1 – 26.2
Unsupervised child ingestion	946	4,871	21.2	18.4 – 24.0
Excess dose	375	2,330	10.1	8.8 – 11.4
Other	398	2,707	11.8	9.9 – 13.7
Disposition†
Discharged	3,267	20,850	90.6	88.0 – 93.3
Hospitalized	400	2,154	9.4	6.7 – 12.0
Total	3,667	23,005	100.0	N/A

^*National Electronic Injury Surveillance System–Cooperative Adverse Drug Event Surveillance project, CDC.

^†For definitions please see Table S1 in Supplementary Appendix.