Fig. 1.

Percentage of poor growth responders after first-year GH treatment in prepubertal children according to various criteria in SGA and GHD patients. SGA = small for gestational age; GHD = growth hormone deficiency; SDS = standard deviation score; ∆Ht = first-year gain in height; HV = height velocity; SR = studentized residual. * HV < − 1 SD for expected first-year treatment response based on reference data developed by Ranke et al. ^# p < 0,01 vs. ∆Ht SDS < 0.3, HV SDS < 0.5, SR < − 1, HV Ranke SDS < − 1; ^@ p < 0,05 vs. ∆Ht SDS < 0.3, HV SDS < 0.5, HV Ranke SDS < − 1