Table 2.

First-year response and responsiveness to GH treatment

	SGA						GHD (all)						Severe GHD (peak GH < 5 μg/L)						Less-severe GHD (peak GH 5–10 μg/L)
	n	Mean	SD	Median	p25	p75	n	Mean	SD	Median	p25	p75	n	Mean	SD	Median	p25	p75	n	Mean	SD	Median	p25	p75
Response parameters
∆ Height, SDSa	171	0.57	0.26	0.561	0.38	0.77	122	0.83	0.59	0.691	0.47	1.08	66	0.97	0.65	0.88	0.55	1.31	56	0.62	0.41	0.59	0.38	0.74
HV, cm/year	171	8.1	1.5	8.21	7.2	9.2	122	9.4	2.6	9.01	7.6	10.9	66	10.1	2.8	9.9	8.4	12,0	56	8.4	1.9	8.3	7.2	9.5
HV for age and sex, SDS	170	1.98	1.42	2.042	1.01	2.91	105	2.7	2.03	2.522	1.27	3.72	57	3.22	2.33	3.06	1.41	4.9	48	2.09	1.39	2.1	0.97	2.78
Parameters of estimated responsiveness
HV Rankeb, SDS	171	−0.09	0.85	−0.08	−0.67	0.55	118	0,00	0.87	0.04	−0.57	0.53	63	0.03	0.92	−0.02	−0.47	0.64	55	−0.04	0.81	0.04	−0.58	0.37
Studentized residual	159	−0.12	0.94	−0.02	−0.7	0.5	113	−0.35	1.13	0.263	−0.89	0.2	60	−0.43	1.3	−0.4	−0.93	0.3	53	−0.25	0.9	−0.16	−0.89	0.17

SGA small for gestational age, GHD growth hormone deficiency, GH growth hormone, HV height velocity; ^again in height SDS after first-year GH treatment; ^bKIGS growth targets for first-year GH response; ¹p < 0,001; ²p < 0,05; ³p < 0,05 vs. zero