Table 1.

Overlap between sex-specific NAFLD subnetworks and DEGs affected by sex hormones

Tissue	Sex	Network size	DEG size	Overlap gene size (overlap KD size)	Overlap KD list	Fold change	P value
Liver	M	218	2435	100 (14)	C8B, CYP7B1, SLC16A7, SLC16A5, CD36, MGST3, NCKAP1L, INPP5D, ANXA2, HCK, FCER1G, FGL2, CIDEC, TBC1D15	6.13	8.28E−71
	F	86	196	2 (0)	–	3.86	8.68E−02
Adipose	M	261	1804	71 (8)	FASN, AACS, ETFDH, GYS1, ECHS1, SH3D21, SLC2A3, PMEPA1	4.39	9.34E−35
	F	206	1491	34 (5)	MSLN, GPM6A, PTGIS, RSPO1, BNC1	3.22	4.57E−13

One-sided Fisher’s exact test was used to calculate enrichment P values