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Comparison of clinical isolates to laboratory-evolved isolates. Each point represents the multivariate (Mahalanobis) distance between a clinical strain and the distribution of all individual isolates from replicate populations in each treatment. Mahalanobis distances are calculated for all traits (A) and excluding antibiotic resistance (AR) traits (B). Black circles are nonepidemic clinical isolates, and gray circles are epidemic isolates. Solid lines represent treatment means.
