Table 3.
Cell line | Retreating from an approaching neighbor, % | Following a retreating neighbor, % |
MDCK epithelial cells | 83.6 ± 3.7 (n = 91)*** | 75.7 ± 5.0 (n = 74)*** |
NIH 3T3 fibroblasts | 86.3 ± 4.9 (n = 51)*** | 70.0 ± 7.3 (n = 40)* |
The majority of cells stalled at an X intersection initiated migration within 1.5 h upon contact with a migrating cell, either away from an approaching cell or toward a retreating cell. Numbers indicate the percentage of cells stalled at an X intersection that initiated directional migration upon contact with a migrating cell. Significance was determined using a one-sample binomial test against the null hypothesis of equal probability of entering any branch. *P < 0.05, ***P < 0.0005.