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. 2018 Oct 1;115(42):10786–10791. doi: 10.1073/pnas.1809285115

Table 1.

Effect of copper on the MIC of ampicillin (µg/mL) against E. coli and E. faecium strains

CuCl2 (mM) E. coli BW25113* E. faecium*
WT (none) M1 (LDT) pTRC99aΩ blaTEM116 (β-Lactamase) M512 (LDT) D344R (PBP5)
0 8 128 >512 512 32
0.25 8 64 >512 512 32
0.5 8 64 >512 512 32
1 16 8 >512 512 32
2 8 8 >512 4 32
4 16 16 >512 8 64
8 32 32 >512 8 512

The values are medians of five independent experiments.

*

The resistance mechanism of strains is in parenthesis.