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. 2018 Oct 22;10:127. doi: 10.1186/s13148-018-0555-3

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Differential methylation of CpG sites in gene bodies and promoter regions. a Frequency distribution of differentially methylated CpG sites in TCGA HM450 data is shown as a percentage of all CpG sites on each human chromosome. b Number of genes with differentially methylated CpG sites in either promoter or gene body regions at varying thresholds