Table 1.
Study ID | Type of sleep deprivation | Duration of sleep deprivation (h) | Species | Brain region |
---|---|---|---|---|
Basheer, 1999[13] | Complete, Gentle Handling | 3 | Rat | BF |
Blanco-Centurion, 2006[14] | Complete, Gentle Handling | 6 | Rat | BF |
Kalinchuk, 2011[27] | Complete, Gentle Handling | 11 | Rat | BF & cortex |
McKenna, 2007[15] | Sleep Interruption, forced locomotion | 6 or 24 | Rat | BF |
Murillo-Rodriguez, 2008[16] | Complete, Gentle Handling | 6 | Rat | BF |
Porkka-Heiskanen, 2000[26] | Complete, Gentle Handling | 6 | Cat | BF & cortex |
Vazquez-DeRose, 2014[37] | Complete, Gentle Handling | 6 | Rat | BF |
Wigren, 2007[17] | Complete, Gentle Handling | 8.5 | Rat | BF |
Please note that the gentle handling method of sleep deprivation comprises several experimenter-driven strategies to keep animals awake (e.g. tapping the cages, introducing novel objects, stroking with a brush and sometimes actual handling). Only brain regions included in the meta-analyses are mentioned; either basal forebrain (BF) or BF and cortex.