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. 2018 Oct 9;16:11. doi: 10.5334/jcr.171

Table 1.

Sleep deprivation related study characteristics of studies included in the meta-analyses.

Study ID Type of sleep deprivation Duration of sleep deprivation (h) Species Brain region

Basheer, 1999[13] Complete, Gentle Handling 3 Rat BF
Blanco-Centurion, 2006[14] Complete, Gentle Handling 6 Rat BF
Kalinchuk, 2011[27] Complete, Gentle Handling 11 Rat BF & cortex
McKenna, 2007[15] Sleep Interruption, forced locomotion 6 or 24 Rat BF
Murillo-Rodriguez, 2008[16] Complete, Gentle Handling 6 Rat BF
Porkka-Heiskanen, 2000[26] Complete, Gentle Handling 6 Cat BF & cortex
Vazquez-DeRose, 2014[37] Complete, Gentle Handling 6 Rat BF
Wigren, 2007[17] Complete, Gentle Handling 8.5 Rat BF

Please note that the gentle handling method of sleep deprivation comprises several experimenter-driven strategies to keep animals awake (e.g. tapping the cages, introducing novel objects, stroking with a brush and sometimes actual handling). Only brain regions included in the meta-analyses are mentioned; either basal forebrain (BF) or BF and cortex.