Figure 1.

PD-L1 expression is increased in cancer tissue. (A) Representative images of PD-L1 and LAG-3 expression. Green color represents PD-L1 expression, while red color represents LAG-3 expression. Scale bar, 100 µm. Arrows indicate the positive staining. (B) Quantification data of PD-L1 expression showing that PD-L1 expression in the carcinoma tissue was significantly increased compared with paracancerous tissue. (C) Quantification data of LAG-3 expression showing that LAG-3 expression in the carcinoma tissue was significantly increased compared with paracancerous tissue. *P<0.05 vs. paracancerous tissue. (Paired Student's t-test). PD-L1, programmed cell death ligand 1; LAG3, lymphocyte-activating gene 3.