Table I.
Association between the expression of miR-224-5p between prostate cancer tissue and non-cancerous tissue based on The Cancer Genome Atlas data.
| miR-224 expression | T-test | |||||
|---|---|---|---|---|---|---|
| Clinicopathological parameter | Cases | Mean | SD | FC | T-value | P-value |
| Group | ||||||
| Normal adjacent | 51 | 5.4773 | 0.86449 | 1.0000 | −3.413 | 0.001 |
| Cancer | 498 | 5.0255 | 1.19453 | 0.9175 | ||
| Age (years) | ||||||
| <60 | 204 | 4.9880 | 1.36730 | 1.0000 | −0.086 | 0.931 |
| ≥60 | 296 | 4.9982 | 1.26126 | 1.0020 | ||
| Pathological T stage | ||||||
| T1-T2 | 188 | 5.1306 | 1.21866 | 1.0000 | 1.880 | 0.061 |
| T3-T4 | 305 | 4.9052 | 1.33624 | 0.9561 | ||
| N stage | ||||||
| N0 | 348 | 5.0312 | 1.28350 | 1.0000 | 1.347 | 0.179 |
| N1 | 79 | 4.8182 | 1.19763 | 0.9577 | ||
| M stage | ||||||
| M0 | 456 | 4.9999 | 1.25252 | 1.0000 | 1.715 | 0.087 |
| M1 | 4 | 3.9179 | 1.76728 | 0.7836 | ||
| Gleason score | ||||||
| ≤7 | 291 | 5.1057 | 1.13197 | 1.0000 | 1.143 | 0.254 |
| 8≥ | 203 | 4.9815 | 1.26629 | 0.9757 | ||
| Gleason grade | ||||||
| 2 | 1 | 4.8074 | 1.048 | 0.371 | ||
| 3 | 197 | 5.1616 | 1.12858 | |||
| 4 | 248 | 5.0052 | 1.23926 | |||
| 5 | 48 | 4.8763 | 1.16617 | |||
| Recurrence | ||||||
| No | 373 | 5.0491 | 1.30796 | 1.0000 | 1.008 | 0.314 |
| Yes | 58 | 4.8636 | 1.27528 | 0.9633 | ||
| Clinical T stage | ||||||
| T1-T2 | 351 | 5.0312 | 1.31167 | 1.0000 | −0.338 | 0.735 |
| T3-T4 | 55 | 5.0945 | 1.14167 | 1.0126 | ||
miR, microRNA; SD, standard deviation; FC, fold-change.