Table V.

Characteristics of the expression of microRNA-224-5p between prostate adenocarcinoma and non-cancerous studies.

	Patients			Controls
Study	N	Mean	SD	N	Mean	SD	T-value	P-value
GSE54516	51	4.3588	0.0525	48	4.2649	0.0420	9.858	<0.001
GSE59156	24	3.6686	1.0369	18	4.0963	1.6407	−1.033	0.308
GSE64318	27	3.0859	0.9412	27	2.0776	1.7120	2.682	0.011
GSE76260	32	3.6162	0.0662	32	3.6723	0.0512	−3.794	<0.001
GSE14857	12	5.0417	1.3522	12	5.9110	0.5401	−2.068	0.051
GSE18671	14	6.6809	0.3943	6	6.4473	0.5782	1.057	0.305
GSE21036	114	5.2423	1.0451	28	6.6041	0.9873	−6.243	<0.001
GSE34932	8	2.1788	1.0875	8	3.5600	1.0803	−2.549	0.023
GSE23022	20	0.9755	0.2065	20	1.0201	0.1732	−0.740	0.464
GSE60371	56	6.3003	0.4778	21	6.6752	0.3432	−3.285	0.002
GSE36802	21	4.4416	0.9294	21	5.7362	1.1766	−3.957	<0.001
E-MTAB-408	42	3.2419	1.5142	12	3.7560	1.6093	−1.023	0.311
TCGA	498	5.0164	1.2154	52	5.4589	0.8661	−3.413	0.001
GSE39314	9	7.4306	3.6046	8	10.1763	6.1584	−1.104	0.293
GSE61741	65	4.8860	2.4333	35	5.4507	1.5656	−1.407	0.163
GSE24201	14	3.5766	1.8929	15	3.5814	2.1733	−0.006	0.996
GSE49298	4	5.1792	1.5787	4	4.9743	0.3945	0.252	0.810
GSE17317	9	9.8705	0.1835	3	12.2457	0.5820	−7.559	0.013
Kristensen et al (28)	36	2.5623	0.2523	14	2.9291	0.1469		<0.001
Fu et al (27)	20	1.3444	0.3578	20	2.1705	0.5643		<0.001
Mavridis et al (26)	73	4.2280	0.8090	66	8.4700	2.0900		<0.001
Total		Standardized mean difference (95% CI)=−0.562 (−0.687, −0.436) P<0.001

SD, standard deviation; TCGA, The Cancer Genome Atlas.