Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Sep 28;40(6):3261–3272. doi: 10.3892/or.2018.6745

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Liang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Figure 4. — Upregulated miR-29a suppresses migration, invasion, proliferation and promotes apoptosis of HCC cells. (A) The level of miR-29a in 3 HCC cell lines (Hep3B, HCCLM3 and Huh-7) and a normal liver cell line (HL-7702). (B) The satisfactory transfection efficiency of miR-29a mimics with HCCLM3 cells, and the IFITM3 protein expression in response to the transfection of miR-29a. (C) Wound healing assays indicated that the migration capacity of HCCLM3 cells was decreased after miR-29a upregulation. (D) The invasion and metastatic abilities of HCCLM3 cells were decreased after miR-29a upregulation. (E) EdU proliferation assays demonstrated that the proliferation abilities were significantly decreased in the miR-29a-upregulated HCCLM3 cells than that in the NC groups. (F) The apoptosis rate of HCCLM3 cells transfected with miR-29a mimics was significantly higher than in the NC groups. *P<0.05, **P<0.01, ***P<0.001 compared with the NC groups. NC, negative control; IFITM3, interferon-induced transmembrane protein 3.