Table II.
Signaling pathways and the regulating genes in tangeretin-treated AGS cells using the Protein ANalysis THrough Evolutionary Relationships (PANTHER) database.
| No. | Pathway | Symbol of regulated gene |
|---|---|---|
| 1 | 5-Hydroxytryptamine type 2 receptor-mediated signaling pathway | KPCE |
| 2 | α-adrenergic receptor signaling pathway | KPCE |
| 3 | Alzheimer's disease-amyloid secretase pathway | MK04, KPCE |
| 4 | Angiogenesis | KPCE |
| 5 | Apoptosis signaling pathway | KPCE |
| 6 | Cholecystokinin receptor signaling map | KPCE |
| 7 | Cytoskeletal regulation by Rho GTPase | MYH13 |
| 8 | DNA replication | TOP2A |
| 9 | Epidermal growth factor receptor signaling pathway | KPCE |
| 10 | Endothelin signaling pathway | KPCE |
| 11 | Fibroblast growth factor signaling pathway | KPCE |
| 12 | Gonadotropin releasing hormone receptor pathway | KPCE |
| 13 | Heterotrimeric G-protein signaling pathway: Gqα and Goα-mediated pathway | KPCE |
| 14 | Histamine H1 receptor-mediated signaling pathway | KPCE |
| 15 | Inflammation mediated by chemokine and cytokine signaling pathway | KPCE, MYH13 |
| 16 | Muscarinic acetylcholine receptor 1 and 3 signaling pathway | KPCE |
| 17 | Nicotinic acetylcholine receptor 1 and 3 signaling pathway | MYH13 |
| 18 | Oxytocin receptor-mediated signaling pathway | KPCE |
| 19 | Thyrotropin-releasing hormone receptor signaling pathway | KPCE |
| 20 | Vascular endothelial growth factor signaling pathway | KPCE |
| 21 | Wnt signaling pathway | KPCE, MYH13 |