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. 2018 Sep 26;40(6):3392–3404. doi: 10.3892/or.2018.6736

Table III.

Univariate and multivariate analysis of PFS and OS.

PFS OS


Univariate Multivariate survival analysis Univariate Multivariate survival analysis




Clinicopathological characteristics P-value HR 95% CI P-value P-value HR 95% CI P-value
Sex 0.385 0.584
Drinking 0.536 0.617
Smoking 0.029 1.022 0.496–2.104 0.954 0.040 0.826 0.408–1.671 0.594
Age at diagnosis 0.001 1.595 0.835–3.045 0.157 0.002 1.190 0.597–2.370 0.621
Tumor size 0.019 1.725 0.936–3.176 0.080 0.016 1.659 0.860–3.198 0.131
Lymph node metastasis <0.001 1.603 0.868–2.960 0.132 0.001 1.612 0.831–3.129 0.158
Clinical stage <0.001 2.349 1.268–4.352 0.007 <0.001 2.028 1.075–3.826 0.029
Resistin expression 0.002 1.856 1.003–3.436 0.049 0.007 1.895 1.005–3.574 0.048
Chemoradiotherapy <0.001 0.059 0.013–0.256 <0.001 <0.001 0.027 0.004–0.210 0.001

PFS, progression-free survival; OS, overall survival; HR, hazard ratio; CI, confidence interval.