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CD68-ET3-LV CD34+ study design
| LV source | Sample size | Treatment cell dose | Post-treatment analyses | Post-treatment follow-up duration |
|---|---|---|---|---|
| CD68-ET3-LV (LTG1434) | 4—LV transduced | 106 | CBC | Up to 16 weeks |
| FVIII activity | ||||
| VCN | ||||
| CD68-ET3-LV (pET68-3) | 7—Mock 16—Untreated 22—LV transduced |
106 | CBC | Up to 52 weeks |
| FVIII activity | ||||
| VCN | ||||
| Chemistries (n = 13) |
LV, lentiviral vector; CBC, complete blood count; FVIII, factor VIII.
