Table 2.
Clinical characteristics of 4 subgroups of patients with chronic HBV infection.
IT | IC | LR | RA | p-value | |
---|---|---|---|---|---|
Subjects, n | 19 | 20 | 18 | 20 | / |
Gender, males/females | 10/9 | 12/8 | 11/7 | 12/8 | 0.950 |
Age, y | 29(18-52) | 29(18-56) | 41.5(18-71) | 42(24-65) | 0.002 |
ALT, IU/L | 27(16-38) | 293(85-939) | 25.5(15-34) | 332(57-942) | <0.001 |
AST, IU/L | 28(13-38) | 129(51-491) | 22(19-34) | 177.5(39-915) | <0.001 |
HBV DNA, log10 IU/mL | 7.87(6.45-8.38) | 7.76(3.72-8.23) | 2.36(0-3.20) | 5.51(2.00-8.23) | <0.001 |
HBsAg, log10 IU/mL | 4.557(3.495-4.54) | 3.85(2.85-4.60) | 2.69(1.35-3.53) | 3.32(1.30-4.61) | <0.001 |
HBeAg, positive/negative, n | 19/0 | 20/0 | 0/18 | 0/20 | <0.001 |
ALT, elevated/normal, n | 0/19 | 20/0 | 0/18 | 20/0 | <0.001 |
(a) Values are expressed as median (minimum-maximum) for age, ALT, AST, and HBV DNA.
(b) HBV DNA<100 was treated as 0 log10 IU/ml.
(c) HBsAg<20 was treated as 20.