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. 2018 Oct 16;77(1):1528125. doi: 10.1080/22423982.2018.1528125

Table 1.

Maternal and neonatal cotinine and NNAL concentrations by tobacco product.

  Cigarette (n = 36)
Commercial (n = 9)
Iqmik (n = 16)
 
  GM 95% CI GM 95% CI GM 95% CI p
Maternal Cotinine ng/ml 138.0 87.7 – 217.2 186.8 54.9 – 641.8 204.4 88.9 – 468.6 0.54
Maternal NNAL pg/ml 106.3 71.2 – 158.5 411.6 122.7 – 1372.2 31.5 16.6 – 59.3 < 0.01
Maternal Cotinine ng/mg creatinine 356.4 215.1 – 590.4 337.0 99.6 – 1142.1 735.1 285.5 – 1891.3 0.14
Maternal NNAL pg/mg creatinine 276.1 188.6 – 404 735.1 268.2 – 2024.6 113.3 60.6 – 210.4 < 0.01
Neonate Cotinine ng/ml 55.2 35.7 – 85.3 53.5 13.7 – 210.1 80.6 29.6 – 218.3 0.36
Neonate NNAL pg/ml 15.9 11 – 23 53.5 25.2 – 114.2 5.5 3.0 – 10.1 < 0.01
Neonate Cotinine ng/mg creatinine 215.6 119.5 – 388.8 165.3 26.4 – 1033.5 258.8 70.4 – 951.2 0.7
Neonate NNAL pg/mg creatinine 67.7 41.1 – 111.7 135.1 39.7 – 459.5 24 12.1 – 47.3 0.03
NNAL/Cotinine ng/pg (maternal) 0.7 0.5 – 1.0 2.2 0.9 – 5.4 0.2 0.1 – 0.3 < 0.01
NNAL/Cotinine ng/mg (neonate) 0.3 0.2 – 0.4 0.9 0.3 – 2.8 0.1 0.03 – 0.2 < 0.01

Geometric Mean and 95% CI for levels of NNAL and cotinine measured in neonate and maternal urine. Significance of differences determined by Kruskal-Wallis test