Long noncoding RNAs play key roles in maintenance of HSC homeostasis and development of terminally differentiated blood cells during hematopoiesis. LncRNA genes are listed in red. HSC, hematopoietic stem cell; MPP, multipotent progenitor cell; CMP, common myeloid progenitor; CLP, common lymphoid progenitor; MEP, megakaryocyte erythroid progenitor; GMP, granulocyte macrophage progenitor; EB, erythroblast; MK, megakaryocyte; GC, granulocyte; MF, macrophage; DC, dendritic cell; NK, natural killer; PLT, platelets; RBC, red blood cells.