Table 2.

The final volume tumor volume is shown for the constant-dose treatments according to the patient and the dose per fraction administered (1 Gy < d < 3 Gy) considering the overall tumor [V_t(t_e), upper panel] and the active portion [V_a(t_e), lower panel], respectively.

Patient	d = 1	d = 1.5	d = 1.8	d = 2	d = 2.5	d = 3	c[(d,Vt(te)]	Best treatment
Final overall volume – Vt(te) [%]
A	73.65	48.22	40.27	36.89	32.22	31.04	−0.842	d = 3	hypo
B	20.95	10.80	9.67	10.15	12.27	18.01	−0.495	d = 1.8	strd
C	45.12	29.37	26.53	26.24	27.71	31.35	−0.653	d = 2	strd
D	1.00	1.66	2.42	3.10	5.18	8.32	0.984	d = 1	hyper
E	5.33	9.19	12.67	15.66	22.93	31.71	0.990	d = 1	hyper
F	51.50	28.15	22.83	22.44	23.30	30.36	−0.696	d = 2.5	hypo
G	63.68	47.39	43.16	42.36	42.85	47.61	−0.725	d = 2.5	hypo
Patient	d = 1	d = 1.5	d = 1.8	d = 2	d = 2.5	d = 3	c[d,Va(te)]	Best treatment
Final active volume – Va(te) [%]
A	73.28	47.84	39.96	36.49	31.80	30.44	−0.883	d = 3	hypo
B	19.54	8.56	7.34	7.07	8.18	10.48	−0.515	d = 2	strd
C	44.52	28.09	25.29	24.54	26.00	29.41	−0.571	d = 2	strd
D	0.88	1.48	2.24	2.87	4.87	7.17	0.974	d = 1	hyper
E	4.12	7.21	10.58	13.07	20.06	26.84	0.989	d = 1	hyper
F	49.44	22.32	16.34	13.72	12.18	13.07	−0.794	d = 2.5	hypo
G	62.82	45.31	40.64	38.89	38.38	40.44	−0.754	d = 2.5	hypo

Only three patients (B, D, and E) reached the 80% reduction (final volume <20%), in bold the lowest final volume. The last two columns of both tables show the correlation between the dose per fraction and the tumor at the end of irradiation (t_e) and the best treatment according to the lowest final volume criterion. Considering either the active or total volume the optimal treatment changes only for patient B as underlined.