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. 2018 Oct 22;8:15592. doi: 10.1038/s41598-018-34048-9

Table 1.

Between-group comparison of gray matter volume and correlations between gray matter volume and genetic and clinical measures.

Clinical data Gray matter region Hemi- sphere r-value (p-value) Volumea (SE) P-value
HC DM1
CTG repeat Middle occipital sulcus and lunatus sulcus L −0.633 (0.005)** 1.426 (0.08) 1.154 (0.06) 0.008**
R −0.528 (0.024)* 1.297 (0.06) 1.024 (0.07) 0.005**
Lateral orbital sulcus R −0.563 (0.015)* 0.638 (0.04) 0.478 (0.03) 0.002**
Posterior ramus of the lateral sulcus R −0.530 (0.024)* 1.878 (0.05) 1.714 (0.05) 0.018*
Hand grip Opercular part of the inferior frontal gyrus L 0.568 (0.014)* 2.863 (0.08) 2.947 (0.16) 0.632
Triangular part of the inferior frontal gyrus L 0.731 (0.001)** 2.393 (0.08) 2.249 (0.12) 0.326
Superior occipital gyrus L 0.652 (0.003)** 2.484 (0.10) 1.916 (0.08) <0.001**
Superior part of the precentral sulcus L 0.485 (0.041)* 2.147 (0.12) 1.697 (0.08) 0.004**
Parcentral lobule and sulcus R 0.491 (0.038)* 2.200 (0.07) 2.002 (0.10) 0.102
Postcentral gyrus R 0.493 (0.038)* 3.399 (0.10) 2.985 (0.13) 0.013*
Anterior transverse temporal gyrus R 0.589 (0.010)* 0.749 (0.04) 0.623 (0.04) 0.031*
Inferior segment of the circular sulcus of the insula R 0.546 (0.019)* 1.912 (0.05) 1.745 (0.06) 0.028*
Middle occipital sulcus and lunatus sulcus R 0.471 (0.048)* 1.297 (0.06) 1.024 (0.07) 0.005*
Caudate L 0.638 (0.004)** 3.343 (0.09) 3.215 (0.13) 0.423
R 0.537 (0.022)* 3.525 (0.09) 3.435 (0.14) 0.580
Amygdala L 0.477 (0.045)* 1.634 (0.06) 1.374 (0.05) 0.002**
Accumbens L 0.511 (0.030)* 0.633 (0.03) 0.452 (0.03) <0.001**
Disease duration Brain stem −0.598 (0.009)** 18.651 (0.43) 17.014 (0.37) 0.007**

aUnit of volume: ml; * and **indicate p < 0.01 and p < 0.05, respectively.