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. 2018 Oct 22;8:15572. doi: 10.1038/s41598-018-33629-y

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

The Promoter Methylation Levels of BLAT1 and EN1 Are Associated with Clinical Outcomes. (A,B) The Kaplan–Meier estimator shows poor overall survival in patients with lower levels of the BLAT1 (beta value < 0.2) (A) and EN1 (B) promoter methylation, compared to those with higher levels of methylation (beta value > 0.2) (p = 0.034 and p = 0.026, respectively). (C) Patients with higher expression of BLAT1 (>median) have worse survival than those with lower expression (<median) of BLAT1 (p = 0.028).