Table 5.
Toxicities of induction chemotherapy and radiotherapy.
| Toxicities | Toxicity Grade | P value | ||||
|---|---|---|---|---|---|---|
| 0 | 1 | 2 | 3 | 4 | TPF vs GP | |
| The toxicities of IC | ||||||
| Leukopenia | 21 (18.6%) | 21 (18.6%) | 54 (47.8%) | 17 (15.0%) | 0 (0.0%) | 0.189 |
| Thrombocytopenia | 78 (69.0%) | 24 (21.2%) | 7 (6.2%) | 3 (2.7%) | 1 (0.9%) | 0.794 |
| Hemoglobin reduction | 63 (55.8%) | 48 (42.5%) | 2 (1.8%) | 0 (0.0%) | 0 (0.0%) | 0.176 |
| Nausea and vomiting | 55 (48.7%) | 49 (43.4%) | 8 (7.1%) | 1 (0.9%) | 0 (0.0%) | 0.179 |
| Diarrhea | 106 (95.6%) | 4 (3.5%) | 1 (0.9%) | 0 (0.0%) | 0 (0.0%) | 0.203 |
| Hearing loss | 110 (97.3%) | 3 (1.8%) | 1 (0.9%) | 0 (0.0%) | 0 (0.0%) | 0.523 |
| Rash | 97 (85.8%) | 13 (11.5%) | 3 (2.7%) | 0 (0.0%) | 0 (0.0%) | 0.414 |
| Alanine aminotransferase | 80 (70.8%) | 27 (23.9%) | 6 (5.3%) | 0 (0.0%) | 0 (0.0%) | 0.125 |
| Aspartate aminotransferase | 89 (78.8%) | 18 (15.9%) | 6 (5.3%) | 0 (0.0%) | 0 (0.0%) | 0.039 |
| The acute toxicities of radiotherapy | ||||||
| Dermatitis | 107 (94.7%) | 3 (2.7%) | 3 (2.7%) | 0 (0.0%) | 0 (0.0%) | 0.114 |
| Mucositis | 84 (74.3%) | 23 (20.4) | 6 (5.3) | 0 (0.0%) | 0 (0.0%) | 0.740 |
| Dysphagia | 99 (87.6%) | 13 (11.5%) | 1 (0.9%) | 0 (0.0%) | 0 (0.0%) | 0.481 |
| The late toxicities of radiotherapy | ||||||
| Xerostomia | 106 (93.8%) | 6 (5.3%) | 1 (0.9%) | 0 (0.0%) | 0 (0.0%) | 0.773 |
| Neck fibrosis | 110 (97.3%) | 3 (2.7%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0.592 |
| Trismus | 112 (99.1%) | 1 (0.9%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0.330 |
| Hearing impairment | 103 (91.2%) | 6 (5.3%) | 4 (3.5%) | 0 (0.0%) | 0 (0.0%) | 0.544 |
| Cerebral injury | 112 (99.1%) | 1 (0.9%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0.330 |
| Cranial nerve palsy | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 1.000 |