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. 2017 Sep 7;51(5):409–415. doi: 10.1016/j.aott.2017.08.001

Table 2.

Meta-analysis of associations between the D13 and D14 alleles of the ASPN polymorphisms and KOA risk.

Comparison Subgroup Type of model Heterogeneity
Odds ratio
I2 (%) PH OR 95% CI POR
D14 versus D13 Overall Random 61 0.004 1.10 0.90–1.36 0.32
Caucasian Fixed 8 0.36 1.05 0.91–1.21 0.49
Asian Random 67 0.01 0.98 0.78–1.23 0.88
D14 versus other alleles
Overall Random 77 0.00 1.30 1.00–1.70 0.06
Caucasian Random 78 0.00 1.26 0.91–1.73 0.15
Asian Random 79 0.001 1.35 0.81–2.26 0.24
D13 versus other alleles
Overall Random 57 0.01 0.93 0.82–1.06 0.33
Caucasian Random 50 0.07 0.90 0.81–1.00 0.06
Asian Random 67 0.01 0.98 0.78–1.23 0.88