Table 4.

Summary outcomes of associations in rs71746744, rs16399, and rs3196378 COL5A1 polymorphisms with tendon injury

Comparison [R] genetic model	Test of association				Test of heterogeneity
	n	OR	95% CI	P a	P b	I2 (%)	AM
rs71746744 [25, 27]
H	3	0.45	0.22–0.95	0.03	0.31	13	FE
R	3	0.57	0.28–1.17	0.13	0.32	12	FE
D	3	0.57	0.39–0.83	0.004	0.70	0	FE
C	3	0.65	0.48–0.87	0.003	0.41	0	FE
rs16399 [25]
H	2	0.26	0.10–0.69	0.007	0.38	0	FE
R	2	0.31	0.12–0.81	0.02	0.40	0	FE
D	2	0.57	0.37–0.88	0.01	0.42	0	FE
C	2	0.58	0.41–0.82	0.002	0.23	30	FE
rs319378 [27, 31]
H	3	0.93	0.58–1.49	0.77	0.76	0	FE
R	3	0.70	0.49–1.01	0.06	0.50	0	FE
D	3	1.22	0.84–1.77	0.29	0.16	46	FE
C	3	0.83	0.67–1.02	0.08	0.22	34	FE

Cut-offs for P^a and P^b are < 0.05 and 0.10, respectively. Values in italics indicate significant associations

H homozygous, R recessive, D dominant, C codominant, n number of studies, [R] References, OR odds ratio, CI confidence interval, P^a p value for association, P^b p value for heterogeneity, AM analysis model, FE fixed-effects