Table 2.

Hemodynamic characteristics of patients with heart failure with preserved ejection fraction classified according to fluid status. Data are presented as mean ± standard deviations.

Variable	Normohydrated (n = 86)	Fluid overloaded (n = 57)	P value
– directly measured parameters
Systolic pulmonary arterial pressure, mmHg	49.3 ± 17.2	57.4 ± 18.6	0.009
Diastolic pulmonary arterial pressure, mmHg	20.9 ± 6.4	23.4 ± 7.4	0.030
Mean pulmonary arterial pressure, mmHg	32.3 ± 9.2	35.8 ± 9.6	0.031
Pulmonary artery wedge pressure, mmHg	19.0 ± 5.8	20.2 ± 6.1	0.214
Cardiac Output, l/min	5.3 ± 1.5	4.7 ± 1.4	0.027
– calculated parameters
Pulmonary pulse pressure, mmHg	28.4 ± 12.7	33.9 ± 14.6	0.019
Transpulmonary pressure gradient, mmHg	13.3 ± 6.3	15.5 ± 7.0	0.052
Diastolic pressure gradient, mmHg	1.9 ± 4.6	3.2 ± 5.1	0.120
Pulmonary vascular resistance, dynes·s·cm−5	209.9 ± 106.8	284.7 ± 182.0	0.002
Pulmonary arterial compliance, ml/mmHg	3.3 ± 1.9	2.3 ± 1.5	0.003
Stroke volume, ml	79.1 ± 24.5	67.0 ± 24.1	0.004