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. 2017 Feb 28;19(3):237–249. doi: 10.1016/j.neo.2016.07.009

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© 2016 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Increased p-Stat3 expression in mouse and human tumors. We performed immunohistochemical analysis of p-STAT3 expression in mouse control kidneys (8A), mutant tumors (8B), human control kidney (8C) and human tumors (8D). Increased expression of p-STAT3 in tumors than in control kidneys was observed, and RPPA (8E) analysis of human tumors also showed upregulated expression of STAT3 (marked with orange rectangular box). The expression of these genes in each compartment is visualized as a heat map. Red indicates upregulated genes and green indicates down-regulated genes.