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. 2017 Feb 28;19(3):237–249. doi: 10.1016/j.neo.2016.07.009

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© 2016 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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More pronounced Th2 induced cytokine response than Th1 response in the tumors. T-helper cell (Th) response analysis by flow cytometry in the mouse tumors showed that the Th2 induced cytokine response was greater than the Th1 and Th17 responses (Figs. 10A and B). The qPCR analysis showed that the inflammatory cytokines responsible for the Th2 response (Figs. 6D-I) and the Treg response to a maximum extent (Figs. 6A-C) were also upregulated. All data are shown as mean ± SEM, n = 5–6 mice/group (*** P< .001, ** P< .01).