Table 4.
Functionalization | Advantage |
---|---|
PEGylation | stabilization enhanced, circulation time improved, prevention of protein absorption |
Targeting | gene target efficacy in vivo enhanced |
Stimulus response | gene target efficacy in vivo enhanced |
Cell penetrating | cellular uptake enhanced, cross cell membrane |
Endosome escaping | endosomal escaping enhanced, cross cell membrane |
Nuclear localization | nuclear localization |