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. 2018 Sep 19;36:183–195. doi: 10.1016/j.ebiom.2018.09.021

Fig. 6.

Fig. 6

The prognostic value of DEAS in CRC. (a)The DEAS events that simultaneously associated with OS and DFS. Univariate analysis of DEAS on overall and disease-free survival, respectively. Unadjusted HRs (boxes) and 95% confidence intervals (horizontal lines) limited to AS events with P-value <.05. Box size is inversely proportional to the width of the confidence interval. (b) The DEAS events that present with independent prognostic value on survival. Exon Skip (ES), Mutually Exclusive Exons (ME), Retained Intron (RI), Alternate Promoter (AP), Alternate Terminator (AT), Alternate Donor site (AD), and Alternate Acceptor site (AA). Cox regression (univariate and multivariate) was used for data analysis. Likelihood-ratio test was used to determine the P value. All P < .05.