Figure 5.

The Association between Inactivating Mutations in Tumor-Suppressor Genes and Drugs Were Also Obtained Based on the Combination of Observed Responses and Newly Predicted Responses

The association between inactivating mutations in tumor suppressor genes and drugs were also obtained based on the combination of observed responses and newly predicted responses. (A) TP53 is found to be significantly resistant to Nutlin-3a based on the combination of known and unknown response. (B) RB1 is also found to be significantly resistant to PD-0332991.