Table 3.

Treatment interaction with the radiomics score for disease-free survival and overall survival in patients with stage II and III disease.

Radiomics score	Chemo	No chemo	Disease-free survival			Overall survival
			Yes vs No chemo, HR (95% CI)	P	P value for interaction	Yes vs No chemo, HR (95% CI)	P	P value for interaction
Internal cohort (n = 293)
High score	113	85	0.176(0.083–0.374)	<0.001		0.148(0.066–0.333)	<0.001
Medium score	21	25	0.565(0.300–1.065)	0.077	<0.0001	0.717(0.381–1.352)	0.304	<0.0001
Low score	27	22	0.871(0.576–1.318)	0.514		0.806(0.514–1.266)	0.350
External cohort (n = 854)
High score	145	111	0.412(0.306–0.554)	<0.001	<0.0001	0.394(0.293–0.529)	<0.001	<0.0001
Medium score	210	92	0.584(0.412–0.829)	0.003		0.601(0.423–0.854)	0.005
Low score	207	89	0.788(0.489–1.269)	0.327		0.807(0.497–1.309)	0.385

Chemo: chemotherapy.