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Binding affinity profile for (±)-MDMA, R-(−)-MDMA, and S-(+)-MDMA with values for Ki reported in nM ± SEM.247
| Receptor | Hot Ligand | Hot Ligand Activity | (±)-MDMA | R-(−)-MDMA | S-(+)-MDMA |
|---|---|---|---|---|---|
| 5-HT 1 | 3H-5-HT | Agonist | 6,850 ± 1,300 | 4,200 ± 500 | >10,000 |
| 5-HT2 | 3H-Ketanserin | Antagonist | 8,300 ± 1,100 | 3,310 ± 140 | >10,000 |
| D2 | 3H-NMSP | Antagonist | >10,000 | >10,000 | >10,000 |
